Findings indicate two newest TB drugs, bedaquiline and delamanid in combination safe, promising for patients with few options

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A study following outcomes of 28 patients with drug-resistant tuberculosis in three countries with high burdens of the disease found what the researchers cite as strong evidence that a combination of the two newest TB drugs could be part of a safe and effective treatment regimen. The  drugs, bedaquiline — which was approved by the […]

Comprehensive care and support significantly boosts MDR-TB successful treatment completion

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A Taiwan program of comprehensive support and care centered on the needs of patients being treated for multidrug-resistant tuberculosis — at a cost of from $25,000 to $30,000 per patient, per year over the costs of medicines — substantially improved cure rates and drastically reduced rates of patients whose outcomes were unknown, according to a […]

Antiretroviral treatment with treatment for drug-resistant TB evens odds for people with HIV

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People living with HIV achieve rates of survival from drug-resistant tuberculosis similar to those of people without the virus, when they receive immediate access to antiretroviral medicine along with their tuberculosis treatment, a study following more than 200 patients in South Africa found. The findings, pointing to the critical benefits of “aggressive initiation” of life-saving […]

Study reveals biological processes leading to active tuberculosis disease

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Researchers at the University of Cape Town in South Africa have identified a sequence of biological processes that occur as tuberculosis infection progresses to active pulmonary tuberculosis disease. The findings, which demonstrate a clear timeline of biological events that occur between infection and disease, hold important implications for the development of new diagnostics, treatments, and […]

Stigma surrounding tuberculosis keeps patients from services, worsens health risks, but remains largely unmeasured, unaddressed

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Interviews in Kenya, Tanzania and Namibia health facilities found that the more staff knew about patients’ rights, the likelier they were to recognize — and report — discrimination against people with tuberculosis. A study in Lesotho found links between stigma surrounding HIV and TB and increased rates of depression and alcohol use among co-infected patients. […]

48th Union World Conference: Minimally invasive autopsies could fill in the blanks on causes of death

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GUADALAJARA, Mexico – In places where a person can get sick with tuberculosis but never get diagnosed, or get diagnosed, but never treated, with their illness never reported, and where a person can die young without ever coming in contact with a health system, the uncertainties surrounding the true impacts of the TB continue all the […]

48th Union World Conference: In the long path to TB care, competence is among the obstacles

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GUADALAJARA, Mexico – One after another, patients came to clinics and hospitals in rural China complaining of alarming, nagging and debilitating symptoms. They noted  coughs and fevers that didn’t go away, and that they were losing weight for no apparent reason. Their symptoms should have sounded familiar in the health centers of a country with […]

48th Union World Conference: Review finds missed opportunities for preventive therapy for children with HIV in Swaziland

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GUADALAJARA, Mexico – While the vulnerability of children with HIV to tuberculosis has prompted World Health Organization guidelines recommending TB preventive therapy for children with the virus who are over a year old, a review of patient data across 10 years at a Swaziland center providing care to about a fifth of all children with […]

WHO 2017 TB Report: Progress, funding, health coverage all fall short of need to confront impacts of disease

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In 2016, an estimated 10.4 million people worldwide got sick with tuberculosis, and, although the majority of deaths from the disease can be prevented by early diagnosis and treatment,  1.7 million people died of the illness. Only 13 percent of children who should have received preventive treatment to keep them from getting sick with tuberculosis […]

48th Union World Conference: Mozambique community-based group extends TB, HIV outreach

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GUADALAJARA, Mexico – In Mozambique, a country where the burden of HIV and tuberculosis coinfection is high, a community-based organization is bringing services home in an effort to protect people living with HIV from dying of tuberculosis. Working with local health care facilities, and community-based counselors, ADPP works to identify household contacts and sexual partners of […]