Study finds more than 80 percent of patients needing WHO recommended last resort treatment for drug-resistant TB not getting it

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Roughly four years after the World Health Organization recommended that the newest drugs against tuberculosis be made available to patients for whom they represented a last resort, fewer than a fifth of patients needing them have received them, according to a report in the International Journal of Tuberculosis and Lung Disease. The approvals of bedaquiline […]

App addresses nutrition needs of TB patients

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It’s a measure of the time technology takes that now, finally, an app exists to address the wasting that gave tuberculosis its original name — consumption. Leading to malnutrition, serious side effects from drugs or failure to absorb medicines, the serious weight loss that can characterize the disease raises risks of death or recurrence of […]

U.S. Tuberculosis cases drop, but still far exceed numbers set to reach elimination goals

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Two years after noting the first increase in domestic tuberculosis incidence in more than 20 years, the United States Centers for Disease Control and Prevention reported today that new cases in this country are once again continuing to decline — but not nearly enough to reach goals of eliminating the disease and its impacts here […]

Study shows revaccination with existing TB vaccine prevents TB infection later in life

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Getting revaccinated later in life with the same vaccine given to infants to prevent tuberculosis may provide additional protection after the original vaccine loses efficacy, researchers at the 5th Global Forum on TB Vaccines in New Delhi, India, revealed. The Bacillus Calmette–Guérin, or BCG, vaccine is partially effective against preventing TB infection in children for […]

Study indicates that acting on guidelines could avert half of TB cases among children

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Tracing contacts of people confirmed to be sick with tuberculosis and making preventive treatment available to those at risk for the disease, could halve current numbers of TB cases among children in resource limited settings, according to researchers reporting a study of patients across a Kenya rural province. Both of those steps are recommended by […]

Findings indicate two newest TB drugs, bedaquiline and delamanid in combination safe, promising for patients with few options

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A study following outcomes of 28 patients with drug-resistant tuberculosis in three countries with high burdens of the disease found what the researchers cite as strong evidence that a combination of the two newest TB drugs could be part of a safe and effective treatment regimen. The  drugs, bedaquiline — which was approved by the […]

Comprehensive care and support significantly boosts MDR-TB successful treatment completion

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A Taiwan program of comprehensive support and care centered on the needs of patients being treated for multidrug-resistant tuberculosis — at a cost of from $25,000 to $30,000 per patient, per year over the costs of medicines — substantially improved cure rates and drastically reduced rates of patients whose outcomes were unknown, according to a […]

Antiretroviral treatment with treatment for drug-resistant TB evens odds for people with HIV

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People living with HIV achieve rates of survival from drug-resistant tuberculosis similar to those of people without the virus, when they receive immediate access to antiretroviral medicine along with their tuberculosis treatment, a study following more than 200 patients in South Africa found. The findings, pointing to the critical benefits of “aggressive initiation” of life-saving […]

Study reveals biological processes leading to active tuberculosis disease

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Researchers at the University of Cape Town in South Africa have identified a sequence of biological processes that occur as tuberculosis infection progresses to active pulmonary tuberculosis disease. The findings, which demonstrate a clear timeline of biological events that occur between infection and disease, hold important implications for the development of new diagnostics, treatments, and […]