Category Archives: CROI 2014

21st Conference on Retroviruses and Opportunistic Infections, Boston

CROI 2014: With HIV treatment lag for men, life expectancy gender gap widens

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BOSTON, MASS. – When antiretroviral treatment finally came to rural South Africa, it led to one of the fastest life expectancy recoveries in public health history. But men did not benefit equally, according to data presented Thursday by Till Barnighausen from the Africa Centre for Health and Population Studies and the Harvard School of Public […]

CROI 2014: HIV self-testing yields promise in first year of Malawi rollout

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BOSTON, MASS – In the first year that residents in Blantyre, Malawi were offered the option to test for HIV through home, or self-test kits, available through community health worker distribution, vending machines, over the counter in pharmacies and in grocery stores, 76 percent of those given the opportunity to self test took it, and […]

CROI 2014: Sugar daddies? Multiple concurrent partnerships? Studies debunk HIV driver theories that drove responses

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BOSTON, MASS – It is a truth universally acknowledged that a man with a girlfriend several years or more his junior is one of the drivers of South Africa’s HIV epidemic. Similarly, it is a truth long held self evident that a cultural proclivity for having several sexual relationships going at the same time is […]

CROI 2014: PrEP pilots to launch in resource-limited settings

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BOSTON, MASS – Dr. Nelly Mugo from the Kenya Medical Research Institute in Nairobi was able to summarize the use of antiretroviral drugs to prevent HIV acquisition — pre-exposure prophylaxis, or PrEP — in resource limited settings quickly this week. That is because, after a series of clinical trials demonstrating the effectiveness of that prevention […]

CROI 2014: HIV in mothers, infants continues to challenge health, survival

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BOSTON, MASS – On the day that brought an update on the Mississippi baby, who remains free of HIV infection two years after antiretroviral treatment was discontinued, and another baby who tests HIV-negative while continuing early aggressive treatment, CROI presentations also highlighted the challenges HIV presents to birth and survival for mothers and their infants. […]

CROI 2014: Plenary speaker looks at 10 years of Global Fund and PEPFAR and on, urging HIV response be monitored by value of services delivered

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BOSTON, MASS – What is the value of the numbers of people tested for HIV, if the people who actually have the virus are not being tested? What is the value of the identification of the people who do have the virus, if they do not receive treatment? And what is value of the numbers […]

CROI 2014: With “Mississippi Baby” update, news of another infant, case for early intensive HIV treatment progresses

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BOSTON, MASS – The story of the baby born with HIV in Mississippi, treated intensively and immediately, only to be lost to care for five months before turning up healthy, is dominating talk at the Conference on Retroviruses and Opportunistic Infections for a second year, with news that the child continues to show no sign […]

CROI 2014: GeneXpert real world study yields mixed results, highlights SA health system challenges

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BOSTON, MASS – Gavin Churchyard and Katherine Fielding presented results this morning from the XPert for TB: Evaluating a New Diagnostic Trial (EXTEND) on the question of whether Xpert MTB/RIF diagnostic test reduces early mortality in adults with suspected TB, facilitates earlier initiation of TB treatment and antiretroviral therapy and reduces the number of patients […]

CROI 2014: HIV patient deaths, treatment interruptions highlight need to integrate care, strengthen data collection

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BOSTON, MASS – A discussion launched by findings from researchers working in Africa and India Tuesday focused on the quest to keep people living with HIV in care, and on measures to  improve their outcomes. Elvin Geng and colleagues looked at more than 35,000 patients in 14 clinics operated by 5 programs in East Africa […]

CROI 2014: VOICE trial follow shows reported use of products predicted reality “less than a coin toss”

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BOSTON, MASS. – On one hand, researchers had trial participants’ reports that they could, would and had used the products being tested to determine their potential for preventing HIV acquisition — whether pills or vaginal gels — and to back that up they had the unused pills and gel applicators the women returned. On the […]