Category Archives: Research and Development

Biomedical research benefits bring House members, NIH leaders together

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In the face of a proposal by the Trump administration to cut funding for the National Institutes of Health by nearly a quarter with an $8 billion drop, House members hold a hearing that covers “from AIDS to Zika,” the “Cancer Moonshot,” the quest for a universal flu vaccine, how researchers working in their own […]

Semifinalists in NIH/BARDA diagnostic test challenge aim to thwart antimicrobial resistance

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Submissions propose tests to ward of unnecessary, ineffective antibiotic use “Think ‘home pregnancy test’ but for nearly any infectious disease,” — specifically for drug-resistant gonorrhea — one submission proposed, describing a fast, cheap, disposable device that would make diagnosing infectious diseases “almost as simple as taking a patient’s blood pressure.” Another submission described a quick blood […]

WHO calls for list of essential diagnostics

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Last June, a Perspective piece in the New England Journal of Medicine noted the critical place that the World Health Organization’s list of Essential Medicines had assumed in global health policy and responses — donors, governments and insurers were all more likely to invest in promoting accessibility of medicines that were on the list. The […]

From a human-scented mosquito trap to rapid diagnostics, USAID funds research and development against Zika

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Agency picks 21 of 900 ideas from around the world A research center in Tanzania will develop inexpensive sandals treated to ward off mosquito bites. Investigators at Johns Hopkins will create a human-scented trap to lure mosquitoes. In Sao Paolo, Brazil, inventors will make an “intelligent trap” for mosquitoes to improve Zika surveillance. A San […]

While “August is the new September” in accelerated Zika vaccine quest, funding gap could slow momentum, Fauci says

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The first of a planned 80 participants was enrolled Tuesday in a trial to test the initial safety and immune-response-prompting potential for a vaccine candidate to protect against Zika virus infection, with hopes to yield results that will lead to further, larger scale testing beginning in January 2017, Dr. Anthony Fauci said today. The Aug. 1 […]

While Ebola funds dwindle, a study to test treatment for persistent virus begins, and a report cites gaps in outbreak response capacities

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The work of controlling, learning from deadliest Ebola outbreak, preparing for future continues, amid uncertain funding for ongoing responses to crisis A study of men who survived Ebola and have continued to show evidence of the virus in their semen will determine the effectiveness of what Dr. Anthony Fauci hopes will be “another weapon in […]

Zika pregnancy and infant study to seek information on scope of risks from virus, strategies to meet impacts

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And as summer starts in North America, legislators prepare for break . . . //Post updated June 22, 2016 with information on potential environmental factors the study will weigh// Aiming to inform strategies to protect pregnant women and their developing fetuses in Zika endemic areas, a collaborative study by the U.S. National Institutes of Health […]

Malaria vaccine candidate shows longer protection, promise, direction of next steps

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The quest for a vaccine that provides lasting protection against malaria took another step forward today with the release of study results showing a candidate made from a weakened version of the parasite that causes the disease offered protection to five trial participants more than a year after it was administered. The results, while still […]

Report proposes innovative approaches to spurring global health innovations

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In 2003, a study published in the journal Nature told of a vaccine candidate that showed promise against Ebola when tried on monkeys. With funding or financial incentives, and the interest those might have prompted from large pharmaceutical companies, the next step would have been the development of the vaccine for use in humans, Dr. Peter Hotez of […]

Dengue vaccine candidate protects fully in controlled human challenge trial

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Findings, process can further vaccine quests, researchers say An experimental vaccine against dengue completely protected the 21 volunteers  who received it and were subsequently exposed to the virus, while the 20 volunteers who received a placebo instead developed infection after exposure, a study published today in Science Translational Medicine found. Researchers who conducted the human challenge trial say the results bode well […]