Category Archives: TB

With $30 million worth of bedaquiline, drug maker donates 30,000 courses of TB treatment

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Global TB response advocates express continued concern about drug’s price First, a word about the significance of bedaquiline. The first new antituberculosis drug to be developed in nearly half a century, it was given fast-tracked approval by the U.S. Food and Drug Administration at the end of 2012 to speed access to the drug for […]

Beating TB requires more than medicine: The value of patient support

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The following is a guest post by Emily Delmotte of Management Sciences for Health Eight years ago Busisiwe Beko was undergoing treatment for multidrug-resistant tuberculosis when, after months of waiting to see a pediatric specialist, her daughter was diagnosed with the same illness. The five-month-old baby was admitted to a TB hospital where she would […]

45th Union World Conference on Lung Health: Alarm Bells about TB and Diabetes

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BARCELONA, Spain –  The opening press conference of the 45th Union World Conference on Lung Health highlighted a new report calling for international action against the latest co-epidemic, tuberculosis and diabetes. With alarming similarities to the deadly synergy of HIV/TB, the intersection between tuberculosis and diabetes compromises treatment outcomes for both diseases, Dr. Anthony Harries told a packed […]

IDWeek: Some progress in TB drug and diagnostic development, but not enough

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The emerging crisis of multidrug-resistant tuberculosis is a “personal and health system catastrophe” that’s occurring half a million times a year in the form of new cases, Eric Nuermberger said at an IDWeek session on HIV-related opportunistic diseases. Not only is it an intensively difficult disease to treat, requiring up to two years of therapy […]

TB trials highlight needs, opportunities

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Two recently announced tuberculosis study results  could change approaches to treatment delivery and development, but only if funding allows the realization of the opportunities they highlight. One of the studies was the REMoxTB trial, which set out to address the desperate need for shorter, simpler routes to cure tuberculosis, by determining if substituting the antibiotic […]

Xpert use reduced wait for treatment, study shows, but health system, patient challenges remain barriers to full benefits

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The demand for, and the promise of, quick accurate tools to diagnose tuberculosis, and to discover resistance to basic TB treatments, are based on a simple and seemingly irrefutable premise. Such tools, it has been pointed out, make early and effective treatment possible, benefiting both patients and public with faster and more frequent cures, and […]

PaMZ TB drug regimen: Cheaper, simpler, safer and with effectiveness “significantly greater” than standard regimen, researchers say

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An analysis of eight-week data from a clinical trial of a tuberculosis treatment regimen shows the promise of curing the disease in a shorter period of time, at a fraction of the current cost, and with no need for painful injections, researchers at the International AIDS Conference in Melbourne, Australia said Monday. They were announcing […]

Childhood tuberculosis: Study finds larger global hidden epidemic

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Indications of a  “huge undiagnosed reservoir” of pediatric tuberculosis, with actual incidence much higher than the number of cases reported highlight the need for additional study of the disease in children, and an opportunity for improved prevention through household screening, a study released in The Lancet today says. Authors of the study, produced by researchers […]

Linezolid: Affordable generic access win highlights obstacles to life-saving treatment

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With side effects that include stomach pain, vision problems, vomiting, diarrhea,  and anemia as well as pain, weakness, and numbness in hands and feet, linezolid is not something you would take if you had much choice. But for patients in Khayelishta, a township in South Africa’s Western Cape where rates of poverty, HIV and tuberculosis […]

Tuberculosis panel: U.S. effort must focus, prioritize, coordinate

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With the resources allotted to fight tuberculosis worldwide inadequate to demands of a pandemic complicated by drug-resistant strains and the impact of HIV globally, the United States will need to better lead, coordinate, focus and prioritize its efforts, or risk seeing domestic and international goals compromised. That is among the conclusions of a summary report […]