Category Archives: Drug Resistance

TB Week: Integration, involvement, a “holistic” approach key to linking women and tuberculosis care

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When a week of events focusing on the worldwide impact of tuberculosis brings together a group to talk about women’s health and diplomacy, it needs to be a broad-based group, and it was. For a start, the talk at the Washington Club in Washington, DC was sponsored by The Center for Global Health and Diplomacy, [...]

TB Week: Survivors and allies recount illness, treatment, and loss

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In the week leading up to International Tuberculosis Day, which commemorates the discovery by Robert Koch of the cause of the disease in 1882, Science Speaks will look at issues, events and efforts to confront this lasting and global health threat. When South African nurse Pat Bond got sick in 2010, doctors treated her for [...]

Entrepreneur uses cell phones to fight counterfeit drugs while linking patients with answers

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“In healthcare we have to work with what’s already happening” Nathan Sigworth was a freshman in college when he spent a month visiting a small hospital in India, and made a simple discovery: economics there dictated a very different delivery of health care than he was used to seeing. In time, he discovered that while [...]

IOM report looks at global scope of fake and substandard drugs, while study zeroes in on TB impact

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The report released this morning by the Institute Of Medicine portrays a global and growing danger that is both deadly and resource draining, brings the highest risks in the poorest countries, and threatens affluent countries as well. Still, coordinated efforts to tackle the proliferation of fake and substandard medicines lag far behind other efforts to [...]

CDC report on U.S. TB drug shortage reflects local and global challenges

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With no medicine on hand, a father and his infant who have just been diagnosed with multidrug-resistant tuberculosis go untreated, the delay prolonging their recoveries as well as the time they will remain infectious. The delay adds to the risk that they will get sicker and resistant to more drugs, increases the odds that those [...]

FDA TB drug approval a milestone, with caveats

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The U.S. Food and Drug Administration’s approval of the first new drug to treat tuberculosis in nearly half a century and the agency’s first use of its accelerated approval process to speed availability of TB medicine comes with cautions, and with a direction of work yet to be done, agency officials and treatment advocates agree. [...]

TB drug trial yields gains in drug-resistant disease treatment

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A study following patients who had  participated in a trial of a potential new treatment for drug-resistant tuberculosis has shown heartening results, with nearly three-quarters of patients who took the medicine for six months or longer showing “favorable outcomes”  — cured  or completed treatment –  according to a study published in the European Respiratory Journal. [...]

Collaboration seeks to speed new TB treatments

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About half a century has passed since a new tuberculosis drug was put to use, and in that time the challenges to successful treatment of the disease have only grown, with bacteria adapting faster to conditions that allowed it to flourish than science and funding for research. Morphing into forms that require from months to [...]

Study reveals effective preventive dose, pain drug for tuberculosis treatment, bad news and new steps in Uganda . . . and more

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New approaches to disease treatment and prevention, as well as failures in old approaches are part of what we’re reading this week . . .   NIH-Funded analysis estimates effective PrEP dosing for men who have sex with men: An analysis of data from the iPrEx study looked at the amount of the antiretroviral medicine [...]

TB advocates respond to Global Fund proposal for “historical disease allocation” model

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As board members of the Global Fund to Fight AIDS, Tuberculosis and Malaria prepare to meet Thursday and Friday in Geneva, advocates for tuberculosis detection, treatment and prevention have signed a response to a proposal they say will foster a divisive “disease against disease” approach to funding, and seriously undermine efforts to roll out cost-effective [...]