Tag Archives: drug-resistant TB

Drug-resistant TB spreading more easily, amfAR makes case for global AIDS funding, Zambia considers condoms in prisons, and more . . . we’re reading the facts behind the arguments

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Russia’s drug-resistant TB spreading more easily – The mutations making some tuberculosis strains in Russia resistant to treatment may also be improving the ability of the bacteria to spread, an analysis reported in Nature tells us. Researchers are quoted calling the findings “Truly scary,” but also noting that a strong programmatic response could still be […]

As WHO TB report shows 3 million undiagnosed and cites drug-resistance “public health crisis,” physicians urge Obama to increase funding

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Three million people sick with tuberculosis go undiagnosed each year, while failures to address strains of disease that don’t respond to drugs constitute a public health crisis, according to the World Health Organization’s just released 2013 Global Tuberculosis Report. While the report cites progress in continued drops in TB incidence and deaths, it emphasizes that […]

CDC report on U.S. TB drug shortage reflects local and global challenges

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With no medicine on hand, a father and his infant who have just been diagnosed with multidrug-resistant tuberculosis go untreated, the delay prolonging their recoveries as well as the time they will remain infectious. The delay adds to the risk that they will get sicker and resistant to more drugs, increases the odds that those […]

Good Participatory Practice TB drug trial guidelines lay groundwork for research, use of new treatments

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If you consider all the years that time stood still in the world of tuberculosis drug research, the most compelling aspect of the Good Participatory Practice Guidelines for TB Drug Trials just released by a Critical Paths to TB Drug Regimens working group is that occasions exist for them to be used. With nearly half […]

Why response to drug-resistant tuberculosis lags, deadly disease in Togo prisons, while science leaps money lags . . .

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Tuberculosis, Drug Resistance, and the History of Modern Medicine: From what may have been the first published randomized clinical drug trial, to  neglect when deaths declined in the affluent countries where “headlines are written,” to the widening fault lines that divided those who had to worry about tuberculosis, and those who could ignore it, to […]

Alarming but not surprising drug-resistant TB rates, survival sex, “a kind of truce,” and more . . .

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Resistance to second-line drugs in people with multidrug-resistant tuberculosis in eight countries: This Lancet article looking at rates of  resistance to second line anti-tuberculosis drugs in Estonia, Latvia, Peru, Phillipines, Russia, South Africa, South Korea and Thailand, put numbers on a situation already known: tuberculosis is growing harder to cure. Following a June New England […]

Researchers, actress agree: Following past lapses, future in TB, HIV prevention promising, challenging

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In the giddy talk of a turning tide and the chance for an “AIDS-free generation,” a look at the recent history of responses to tuberculosis, the science surrounding that disease as it stands now, and what, after a period of premature complacency in the middle of the last century, yet is to be done to […]

WHO’s TB chief: ‘We have to be bold’

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Dr. Mario Raviglione has been the director of the World Health Organization’s Stop TB Department since 2003. He spoke with John Donnelly about his frustrations with detecting cases of multidrug-resistant TB as well as with delays in accomplishing widespread availablity of the GeneXpert machine, which can detect drug-resistant TB in two hours, compared to two […]

CDC looks at TB/HIV syndemic, Lancet looks at expectations for Jim Kim, studies look at lower HIV risks for gay fathers, importance of healthy vaginas, and more. . .

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CDC’s Grand Rounds feature examines past, future of HIV/TB response: In a world where an estimated 160 people die of tuberculosis every hour, where 25 percent of HIV/AIDS-related deaths are caused by TB, and where 9 million people can be expected to develop the disease each year, while untreatable forms of infection have emerged, “much […]

XDR Becoming More Resistant: "We Will Run Out of Letters Soon"

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Last week, the Global Center released a new issue brief on drug-resistant TB to mark World TB Day. Included in the brief was this interview with Dr. Sarita Shah, who recently presented new research showing that strains of extensively drug-resistant TB (XDR-TB) in Tugela Ferry, South Africa, are becoming more resistant. Tugela Ferry is ground […]