Tag Archives: MDR-TB

CDC U.S., global TB data highlight worldwide needs for extended screening, preventive treatment, access to newest medicines

By on .

Releasing the most recent domestic and global data on tuberculosis incidence in this week’s Morbidity and Mortality Weekly Report, the U.S. Centers for Disease Control and Prevention emphasized that while rates of new cases continue to drop, they are not declining swiftly enough to reach important and achievable goals. Those goals include ones agreed to […]

WHO finalizes MDR-TB treatment guidance recommending shift from injections

By on .

Including recommendations that injected drugs with permanent debilitating side effects not be included in longer treatment regimens against multidrug-resistant tuberculosis, and the inclusion of the most recently added drugs, bedaquiline and delamanid in those treatments, the World Health Organization today released updated guidelines for treating TB that does not respond to first line treatments. The […]

STREAM Trial: Nine-month regimen for drug-resistant tuberculosis brings “promising cure rates”

By on .

A randomized, multi-country clinical trial testing a regimen for treating drug-resistant tuberculosis in less than a year against the up to two-year regimen recommended by the World Health Organization in 2011 guidelines, substantiates earlier observed findings showing comparable success rates between the two. The STREAM trial (Standard Treatment Regimen of Anti-Tuberculosis drugs for patients with […]

Stalled funding, policies of 2018 pose continuing challenges to infectious disease responses ahead

By on .

A year that started with a shutdown of the U.S. government is ending the same way, demonstrating ongoing instability in American policy, funding and global health leadership. At the same time, from events dividing the ranks of global HIV responders, to the first Ebola outbreak fought in a war zone, the year has highlighted needs […]

What we’re reading: Saying goodbye to gay sex bans, providing safe injection, following WHO guidelines, preventing HIV, treating TB

By on .

In the midst of stalled funding and politicized policies, we’re reading about answers to infectious diseases that remain just out of reach . . . Inspired by India, Singaporeans seek to end gay sex ban – Anti-gay laws imposed across the British Empire remain one of the key barriers to controlling HIV as a global […]

WHO releases updated drug-resistant TB guidelines, removing toxic injectables from recommended treatments

By on .

With the release of a “pre-final text” of updated guidelines for treatment of multidrug- and rifampicin-resistant tuberculosis, the World Health Organization made official substantial changes to its recommendations that the agency first announced in August. The changes, announced in a “rapid communication,” which the WHO said was intended to give TB programs time to plan for […]

With TB now No. 1 global infectious disease killer, USAID justifies cuts to global TB funding

By on .

When House Appropriations Committee members in 2014 asked then USAID Administrator Raj Shah how the U.S. could combat tuberculosis globally with 19 percent less money, he said not to worry. The Global Fund to Fight AIDS, TB and Malaria, and the President’s Emergency Plan for AIDS Relief would fill the gap, he said. Two years […]

TB diagnostic tool development and access remain first obstacles to finding and treating tuberculosis where it poses greatest threats

By on .

In the obstacle course that detecting, treating and curing tuberculosis can present to populations most affected by the disease, the first hurdle, caused by gaps in technology appropriate to realities where the disease flourishes, remains diagnosis. In turn, obstacles to developing diagnostic tools and getting them on the ground, include lack of resources to test […]

Xpert use reduced wait for treatment, study shows, but health system, patient challenges remain barriers to full benefits

By on .

The demand for, and the promise of, quick accurate tools to diagnose tuberculosis, and to discover resistance to basic TB treatments, are based on a simple and seemingly irrefutable premise. Such tools, it has been pointed out, make early and effective treatment possible, benefiting both patients and public with faster and more frequent cures, and […]

As WHO TB report shows 3 million undiagnosed and cites drug-resistance “public health crisis,” physicians urge Obama to increase funding

By on .

Three million people sick with tuberculosis go undiagnosed each year, while failures to address strains of disease that don’t respond to drugs constitute a public health crisis, according to the World Health Organization’s just released 2013 Global Tuberculosis Report. While the report cites progress in continued drops in TB incidence and deaths, it emphasizes that […]