Category Archives: Research and Development

START findings highlight treatment divide

By on .

“It’s just more scientific evidence to back what we’ve been saying for a long time.” Dr. Anthony Fauci, Director, National Institute of Allergy and Infectious Diseases, announcing the conclusion of the START trial, which began in 2011 to assess “the best time for healthy HIV-infected people to begin antiretrovirals.” The announcement from the National Institute […]

START Trial data support starting antiretroviral treatment for HIV as early as possible

By on .

An international trial has shown that starting antiretroviral treatment for HIV early significantly lowers risks of serious illnesses, including AIDS, compared to waiting for immune cell counts to drop. The START — Strategic Timing of AntiRetroviral Treatment clinical trial — which enrolled 4,685 people living with HIV at 215 sites across 35 countries over the […]

Large-scale study underscores value of routine Xpert testing on TB, MDR TB case finding

By on .

A study of more than 100,000 patients with suspected tuberculosis at 18 sites across India showed that routine testing using Xpert molecular technology rather than the most commonly used — and oldest — diagnostic tool of examining a sputum smear under a microscope, increased detection of TB by 39 percent and led to five times […]

Budget cuts threaten HIV vaccine development, say experts

By on .

New HIV infections would decrease by 40 percent within ten years after the launch of an HIV vaccine, experts said at an HIV Vaccine Awareness Day event on Monday hosted by AVAC, IAVI and the Bill and Melinda Gates Foundation. Advancements in technology have paved the way for an effective HIV vaccine, but progress is threatened […]

A research renaissance, the landscape and the art of science . . . We’re catching up on research for HIV Vaccine Awareness Day

By on .

Defeating the Virus – Why a vaccine is necessary, why the quest is complicated, and why different approaches are yielding promising signs are all addressed in this Scientist Magazine piece by International AIDS Vaccine Initiative Chief Scientific Officer Wayne C. Koff. The Trimer Transformed – If you are not a scientist, and if your first obstacle […]

First all-oral XDR-TB drug regimen trial launches in South Africa

By on .

The TB Alliance Wednesday announced the launch of the first clinical trial testing an all-oral regimen to treat extensively- drug resistant tuberculosis. With a three drug combination the Nix-TB regimen trial seeks to cure patients within six to nine months. The trial will launch at three sites in South Africa and will include patients as […]