Monthly Archives: October 2020

COVID-19: When will FDA convene an independent advisory committee for monoclonal antibody EUAs?  

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By Daniel R. Lucey M.D., MPH, FIDSA Rapidly evolving events regarding studies of monoclonal antibodies reemphasize the call first made here Oct. 19  that the U.S. Food and Drug Administration convene an outside expert advisory committee ASAP to advise on requests for Emergency Use Authorization for monoclonal antibodies against SARS-CoV-2. On Oct. 7 Lilly announced […]

To End the HIV Epidemic among Latinx populations, look at the big picture and zoom in

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By Dr. Vincent Guilamo-Ramos and Dr. Barbara Taylor In February 2019, the federal government updated national HIV goals to end the epidemic in the U.S. by 2030. Those goals appeared to be coming into reach because of significant overall progress in the fight against HIV, with deaths attributed to HIV across the U.S. decreasing by approximately 4% […]

IDWeek 2020: Smallpox eradication offers lessons 40 years on, but they’re not easy

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Four decades after it was made official, the eradication of smallpox remains a unique achievement. It is an achievement that stands as proof that a disease meeting the right biological criteria can, with the right strategy, be wiped from the face of the earth. But while attempted, it has not been duplicated. Nor, on examination, […]

IDWeek: A talk examines micro-epidemics, and the elusive solutions they require

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At a conference dominated by discussion of a coronavirus pandemic that, circling the globe, has led to the infections of more than 41 million people and killed more than a million, Dr. Judith Feinberg this week came to talk about a smaller scale public health challenge in a talk titled “HIV Micro-Epidemics: When HIV Comes […]

The 51st Union Conference on Lung Health: Race to secure COVID-19 vaccine doses leaves most countries behind

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The United States is lagging behind other high-income countries in cutting deals with COVID-19 vaccine developers for doses of vaccine per capita, scientists at the 51st Union World Conference on Lung Health showed. With 48 candidate vaccines currently in human clinical trials globally, countries and multilateral organizations are in a race to secure enough doses […]

IDWeek 2020: A look at HIV, COVID-19 in America highlights the role of racism as a vector of infectious diseases

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The 2020 Edward H. Kass Lecture: “All policy is health policy” When the disparate and damaging impacts of HIV and AIDS on Black Americans across the United States finally began to draw notice in the late 1980s and early ’90s, the recognition came with an assumption. Those most affected by the epidemic, common wisdom had […]

IDWeek 2020: Dr. Frieden, WHO’s Dr. Ryan wrap up “Chasing the Sun” with a look at COVID-19 as a long term public health threat

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Get to know this new coronavirus well. “”We’re not halfway through it,” Dr. Thomas Frieden, former director of the U.S. Centers of Disease Control and Prevention said, in the concluding session of “Chasing the Sun,” a 24-hour global view of the pandemic that opened IDWeek 2020’s virtual gathering of infectious diseases specialists worldwide. Calling the […]

The 51st Union Conference on Lung Health: Four-month regimen cures TB as well as standard six-month treatment course

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A shorter four-month drug regimen to treat tuberculosis is as safe and effective as the standard six-month regimen in curing drug-susceptible TB, researchers presented at the 51st Union World Conference on Lung Health being held virtually this week. The shorter regimen – the first successful short treatment regimen for TB identified in more than 40 […]

Will the Oct. 22 FDA COVID-19 vaccine EUA meeting discuss the statistical basis for requiring at least five severe cases in placebo group of Phase 3 vaccine studies? 

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By Daniel R. Lucey M.D., MPH, FIDSA In reference to potential enhanced respiratory disease associated with COVID-19 vaccine candidates, the U.S. Food and Drug Administration briefing document for the Oct. 22 public advisory committee meeting on COVID-19 Vaccine Emergency Use Authorization states (on p. 11 of Appendix II): “Sufficient cases of severe COVID-19 among study […]

IDWeek 2020: Dr. Fauci opens “Chasing the Sun” with a view of COVID-19 in the U.S.

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“His advice is honest and rooted in sound science,” former President George W. Bush “He’s the guy I’ve gone to since 1993 . . . and still do,” National Institutes of Health Director Dr. Francis Collins “Thank you for what you do and who you are,” World Health Organization Director-General Tedros Adhanom Ghebreyesus The former President […]