New TB drug approval a milestone, all agree — with caveats, some add

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The announcement Wednesday of U.S. Food and Drug Administration approval of pretomanid, a new tuberculosis drug that has been part of a ground-breaking treatment regimen against the deadliest and most resistant form of the disease represented a major step forward on multiple fronts, international treatment advocates agree. One of only three new drugs receiving regulatory […]

Activist confronts the “father” of drug-resistant TB

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The following is a guest post by Abigail Mudd, MPH A human rights lawyer and two-time tuberculosis survivor, Timur Abdullaev is an international TB activist. He owes his life, he says, to treatment supported by the Global Fund to Fight AIDS, Tuberculosis and Malaria, and now he also depends on the multilateral initiative for his […]

IAS 2019: Preventing TB — the leading killer of people with HIV — remains tangential to global HIV responses

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MEXICO CITY – In a day-long, pre-conference meeting devoted to addressing tuberculosis prevention among people living with HIV, which continues to account for one in three HIV-related deaths globally, experts discussed the urgent need to listen to communities about their TB prevention needs and offer people-centered interventions. This includes integrating TB prevention services at family planning […]

Global Health Security 2019: Unmet needs increase worldwide threat of drug-resistant TB

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SYDNEY – When Merinda Sebayang was undergoing treatment for multidrug-resistant TB in Indonesia – a nation with the third highest tuberculosis burden in the world after India and China – she would wonder about the tens of thousands of people living in poverty who couldn’t afford enough food for TB treatment to work, she said […]

Thinking strategically about nutrition supports disease responses and more

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The following is a guest post by Heather B. Davis, MPH, and Emily A. Bobrow, PhD, MPH, of MEASURE Evaluation Who has a strategic interest in nutrition? Is the world on course to meet global nutrition targets? What does it mean to have a robust national dialogue to support the development of practical nutrition solutions? […]

CDC U.S., global TB data highlight worldwide needs for extended screening, preventive treatment, access to newest medicines

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Releasing the most recent domestic and global data on tuberculosis incidence in this week’s Morbidity and Mortality Weekly Report, the U.S. Centers for Disease Control and Prevention emphasized that while rates of new cases continue to drop, they are not declining swiftly enough to reach important and achievable goals. Those goals include ones agreed to […]

WHO finalizes MDR-TB treatment guidance recommending shift from injections

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Including recommendations that injected drugs with permanent debilitating side effects not be included in longer treatment regimens against multidrug-resistant tuberculosis, and the inclusion of the most recently added drugs, bedaquiline and delamanid in those treatments, the World Health Organization today released updated guidelines for treating TB that does not respond to first line treatments. The […]

CUGH 2019: Researchers say training, resources for the “private sector,” including traditional healers, will be critical to TB control

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CHICAGO – To find the missing tuberculosis cases that go unreported each year, national TB programs will have to reach out to the places where the most people seek care, researchers said here. And that’s not in public hospitals or clinics where capacities to respond to TB already exist, but in the private sector in […]

STREAM Trial: Nine-month regimen for drug-resistant tuberculosis brings “promising cure rates”

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A randomized, multi-country clinical trial testing a regimen for treating drug-resistant tuberculosis in less than a year against the up to two-year regimen recommended by the World Health Organization in 2011 guidelines, substantiates earlier observed findings showing comparable success rates between the two. The STREAM trial (Standard Treatment Regimen of Anti-Tuberculosis drugs for patients with […]