U = U: The evidence is in. Spreading the word that undetectable = untransmissable is the next crucial step

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By Murray Penner of Prevention Access Campaign Undetectable = Untransmittable, or U=U, is a clear, effective, simple way to convey the fact that a person living with HIV who is on antiretroviral therapy and whose virus is suppressed cannot transmit HIV to sexual partners. In 2016, Prevention Access Campaign, a health equity initiative with the […]

CDC announces publication of TB treatment trial results showing four month regimen as effective as six month

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The publication of trial data showing a four-month treatment regimen for tuberculosis that is not resistant to first-line medicines as effective as the currently widely prescribed six-month regimen will inform guidelines that can significantly ease the burden of the disease on patients, their families, and health services worldwide, the U.S. Centers for Disease Control and […]

Science Speaks wants to hear from you

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Science Speaks, the global infectious disease blog produced by the Infectious Diseases Society of American and its HIV Medicine Association, is seeking input from its readers on how we can best keep you posted on breaking news and analysis of infectious diseases developments around the world. Your answers to a brief survey will help us […]

Seychelles reports rising cases in vaccinated and unvaccinated: Global implications for variants vs. vaccines?

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By Daniel R. Lucey MD, MPH, FIDSA On Tuesday, May 4, the Seychelles news agency reported: “There are currently 1,068 active cases numbers, among which 84 percent are Seychellois and 16 percent are foreigners. Some 65 percent of the active cases are unvaccinated or have received only one dose, whilst the remaining have taken both […]

Merck announces agreement with India for investigational oral drug molnupiravir with potential implications for over 100 countries

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By Daniel R. Lucey MD, MPH, FIDSA On April 27 Merck issued a press release titled, “Amid Humanitarian Crisis in India, Merck Announces Voluntary Licensing Agreements with Five Indian Generics Manufacturers to Accelerate and Expand Global Access to Molnupiravir, an Investigational Oral Therapeutic for the Treatment of COVID-19.” Merck stated that it “has entered into […]

WHO provides update on India’s surging epidemic second wave and variant B.1.617

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By Daniel R. Lucey MD, MPH, FIDSA On April 27 the World Health Organization included in its very helpful weekly epidemiological update on COVID-19 a section on variants, including the one termed “B.1.617” (formerly mis-termed “double mutant”). WHO placed into context the rapidly rising numbers of cases in India with the lower and decreasing numbers […]

Fighting COVID- 19 in Jordan, from early declared victory to extreme burden

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By Mahmoud Shorman, MD, FIDSA, MHA After the reports of the spread of a novel coronavirus in China in the first part of 2020, Jordan was no exception as countries worldwide began putting measures in place to prevent the spread of the virus. By Jan. 26 a protocol designed by Jordan’s Health Ministry with the […]

FDA should convene its vaccine advisory committee for COVID vaccine EUAs for children

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By Daniel R. Lucey MD, MPH, FIDSA On April 9 a request was filed with the U.S. Food and Drug Administration for Emergency Use Authorization of the Pfizer/BioNTech vaccine for 12-15 year olds. Below are four reasons the FDA should convene its Vaccines and Related Biologic Products Advisory Committee (VRBPAC) for all COVID-19 vaccine EUA […]

The COVID Archipelago: Volcanoes and variants

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By Daniel R. Lucey MD, MPH, FIDSA Most archipelagos are created by volcanoes erupting from the ocean floor. Imagining such volcanoes as hotspots of SARS-CoV-2/COVID infections, the virus variants can be imagined as an archipelago of islands above the surface. Each new island has the potential to become its own volcano and spread new variant […]

The COVID variants arrived at the Navajo Nation: Will it be able to stave off the third wave?

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By Kwan Kew Lai, MD, DMD Navajo Nation had its first COVID wave in May of 2020 and on May 18, it quickly surpassed New York as having the highest infection rate. The second wave started in November and by mid-February 2021, it was slowly brought under control. I had the occasion to volunteer with […]