Category Archives: Covid-19/2019-nCoV Dr. Lucey Q&A

Moderna to test a “multivalent” COVID vaccine as well as single-valent boosters

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By Daniel R. Lucey MD, MPH, FIDSA On Wednesday (Feb. 24) Moderna announced a new vaccine strategy against the variant B.1.351 (501Y.V2) now predominant in several nations in southern Africa, and identified in more than 40 nations, as well as multiple U.S. states. Part of this strategy is the first-ever “multivalent” vaccine candidate that “combines […]

Russian and other European H5N8 Avian Flu sequences will inform risk to humans in Astrakhan and beyond

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Vaccine development could also be facilitated By Daniel R. Lucey MD, MPH, FIDSA Now that the H5N8 avian flu virus whole genome sequence that infected seven poultry farm workers in Astrakhan has been shared by Russia in the GISAID database, a search for other locations in Europe and elsewhere with this same sequence can be […]

Russia shared sequence of mutated H5N8 flu infecting humans with GISAID: Will other nations also develop human tests and vaccines?

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By Daniel R. Lucey MD, MPH, FIDSA The Russian News Agency TASS reported on Feb. 20  that Russia had shared the genetic sequence of the mutated H5N8 avian influenza viruses that in December infected seven minimally symptomatic poultry farm workers in Astrakhan, southern Russia. The Global Initiative on Sharing Avian Influenza Data (GISAID) is the […]

Has testing of humans for asymptomatic and mild H5N8 bird flu begun in other nations with H5N8 outbreaks after seven infected workers in Russia’s Astrakhan region?

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By Daniel R. Lucey MD, MPH, FIDSA On Saturday (Feb. 20 ), the Russian news agency TASS reported: “At the beginning of December 2020, an outbreak of bird flu occurred at a poultry farm in Akhtubinsky district . . . During this period, seven employees of the poultry farm had a slight health disorder (sore […]

First-ever human infections with H5N8 bird flu reported by Russia: State laboratory working on a vaccine

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By Daniel R. Lucey MD, MPH, FIDSA Today Russian announced that last December seven workers on a poultry farm in southern Russia were infected with H5N8 bird (avian) flu. Although H5N8 avian influenza (“bird flu”) has been found in several avian species in multiple nations on several continents for more than three decades, it has […]

FDA-USDA statement timely in light of imminent WHO-China COVID-19 team summary

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By Daniel R. Lucey MD, MPH, FIDSA Today this statement (also provided below) from the United States Food and Drug Administration, acting Commissioner Janet Woodcock M.D., and US Department of Agriculture acting Secretary Kevin Shea concluded that there is currently no scientific or epidemiologic basis for the claim that SARS-CoV-2/COVID-19 is transmitted via food or […]

WHO posts global maps of three SARS-CoV-2 variants in 88, 37, and 17 nations: Juxtaposition with a vaccine in South Africa?

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By Daniel R. Lucey MD, MPH, FIDSA Today the World Health Organization posted its weekly epidemiological update, with a special focus on SARS-CoV-2 variants, that contains a world map (below) showing the 37 nations verified to have the 501Y.V2 variant already dominant in South Africa and some neighboring nations. “Local transmission has been reported in […]

Health worker infections and deaths: PAHO COVID-19 data from 18 nations in the Americas

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By Daniel R. Lucey MD, MPH, FIDSA In its Wednesday Feb. 9 epidemiologic update, the Pan American Health Organization published an 18-nation listing of health care worker infections and deaths due to SARS-Cov-2 as of the day before. As seen in the PAHO/WHO table below (page 18 of 21), the largest number of reported infections […]

COVID vaccines in HIV-Positive recipients: Need for more data from the Novavax South Africa study and with other vaccine platforms

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By Daniel R. Lucey MD, MPH, FIDSA The Jan. 28 Novavax press release that included preliminary results from its COVID-19 vaccine Phase 2b trial in South Africa appears to contain a significant difference in efficacy between volunteers who were HIV-positive and HIV-negative. If verified, then the implications warrant sustained attention for this protein-based adjuvanted COVID-19 […]

COVID “Mega-variant” and eight criteria for a template to assess all variants

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By Daniel R. Lucey MD, MPH, FIDSA Building on the Dec. 22 South African variant may be worse than UK variant: A template is needed for the variants to come post here, the following eight criteria are proposed to help create a template to assess the many variant SARS-CoV-2 viruses already found and those to come. […]