Category Archives: IAS2011ROME

The 6th International AIDS Society Conference on HIV Pathogenesis, Treatment and Prevention, Rome.

HIV and TB Co-Infection: A Perfect Storm

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Alberto Matteeli of Italy began his presentation on HIV and tuberculosis (TB) by reminding his audience that in the pre-antiretroviral therapy (ART) era in Europe and the United States, there were serious outbreaks of drug-resistant tuberculosis, and these outbreaks ceased when ART was scaled up in those settings.  There are currently HIV-associated epidemics of multi-drug […]

HPTN 052 “treatment is prevention” study team releases new details

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The presentation of the detailed findings of HPTN 052 by Dr. Myron Cohen, the study’s principal investigator, and his colleagues was greeted with a standing ovation by a packed room at the 2011 International AIDS Conference in Rome on Monday. The stunning finding of a more than 96 percent reduction in transmission risk for discordant couples where the HIV-infected partner was randomized to early antiretroviral therapy (ART) at CD4 counts of 350-550 compared to couples where ART was delayed for the infected partners until CD4 counts dropped to 250 or less, makes ART the most effective prevention intervention identified to date…

IAS 2011 Coverage: Pediatric HIV/AIDS Highlighted on First Day of Conference

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In this guest blog post by Robert Yule of the Elizabeth Glaser Pediatric AIDS Foundation, various sessions on children and HIV and prevention of mother-to-child transmission (PMTCT) are reviewed, including the role of the community in prevention new infections in infants and children plus keeping mothers healthy, the challenges in developing and purchasing new pediatric formulations of antiretrovirals, and the operational and implementation challenges to scaling up PMTCT…

Access to HIV drugs: The good, the bad and the unmet need

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Drug companies are excluding middle-income countries – such as Brazil, Thailand, India, Columbia and China – from HIV drug discount programs where drug prices can be as much as ten times higher, according to a press release and information from a new report by Medecins Sans Frontieres (MSF) released Monday at the 2011 International AIDS […]

A call for clinical trials to evaluate combination prevention

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“There is no silver bullet” is a common mantra in AIDS prevention, and Dr. Robin Shattock of the Imperial College in London provided a plenary talk in that vein on combination prevention Monday at the 2011 International AIDS Conference in Rome.

Shattock defined combination prevention as comprised of four elements—behavior change, treatment, structural interventions and biomedical strategies. Devoted to biomedical strategies, his talk included an outline of interventions that could be implemented prior to HIV exposure—medical male circumcision, oral pre-exposure prophylaxis (PrEP), topical PrEP and preventive vaccines and those interventions relevant subsequent to HIV exposure— antiretroviral therapy (ART), immediate treatment of infected partners and treatment for prevention…

WHO moves forward but does not release new guidance for HIV-discordant couples

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A pre-meeting session at the International AIDS Society conference in Rome was originally expected to feature the release of World Health Organization (WHO) guidance on HIV counseling and testing and access to antiretroviral therapy (ART) for “sero-discordant couples” – where one partner is HIV-infected and the other is not. Instead, the session highlighted a “work in progress” in the context of clinical trial results confirming the efficacy of HIV treatment and pre-exposure prophylaxis (PrEP) using antiretrovirals as HIV prevention…

Africa’s male circumcision programs exceed targets, grow more efficient

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The leader in the medical male circumcision (MMC) campaigns underway in sub-Saharan Africa by far, Kenya has successfully serviced 290,000 men and adolescents in the past 2.9 years. This update came from Dr. Peter Cherutich from the National AIDS and Sexually Transmitted Infections Control Program in Kenya, at a satellite session entitled “The Cutting Edge: What’s New in Male Circumcision,” Sunday evening preceding the 2011 International AIDS Meeting in Rome…