Category Archives: TB

Activist confronts the “father” of drug-resistant TB

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The following is a guest post by Abigail Mudd, MPH A human rights lawyer and two-time tuberculosis survivor, Timur Abdullaev is an international TB activist. He owes his life, he says, to treatment supported by the Global Fund to Fight AIDS, Tuberculosis and Malaria, and now he also depends on the multilateral initiative for his […]

CDC U.S., global TB data highlight worldwide needs for extended screening, preventive treatment, access to newest medicines

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Releasing the most recent domestic and global data on tuberculosis incidence in this week’s Morbidity and Mortality Weekly Report, the U.S. Centers for Disease Control and Prevention emphasized that while rates of new cases continue to drop, they are not declining swiftly enough to reach important and achievable goals. Those goals include ones agreed to […]

WHO finalizes MDR-TB treatment guidance recommending shift from injections

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Including recommendations that injected drugs with permanent debilitating side effects not be included in longer treatment regimens against multidrug-resistant tuberculosis, and the inclusion of the most recently added drugs, bedaquiline and delamanid in those treatments, the World Health Organization today released updated guidelines for treating TB that does not respond to first line treatments. The […]

STREAM Trial: Nine-month regimen for drug-resistant tuberculosis brings “promising cure rates”

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A randomized, multi-country clinical trial testing a regimen for treating drug-resistant tuberculosis in less than a year against the up to two-year regimen recommended by the World Health Organization in 2011 guidelines, substantiates earlier observed findings showing comparable success rates between the two. The STREAM trial (Standard Treatment Regimen of Anti-Tuberculosis drugs for patients with […]

WHO releases updated drug-resistant TB guidelines, removing toxic injectables from recommended treatments

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With the release of a “pre-final text” of updated guidelines for treatment of multidrug- and rifampicin-resistant tuberculosis, the World Health Organization made official substantial changes to its recommendations that the agency first announced in August. The changes, announced in a “rapid communication,” which the WHO said was intended to give TB programs time to plan for […]

TB diagnostic tool development and access remain first obstacles to finding and treating tuberculosis where it poses greatest threats

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In the obstacle course that detecting, treating and curing tuberculosis can present to populations most affected by the disease, the first hurdle, caused by gaps in technology appropriate to realities where the disease flourishes, remains diagnosis. In turn, obstacles to developing diagnostic tools and getting them on the ground, include lack of resources to test […]

Xpert use reduced wait for treatment, study shows, but health system, patient challenges remain barriers to full benefits

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The demand for, and the promise of, quick accurate tools to diagnose tuberculosis, and to discover resistance to basic TB treatments, are based on a simple and seemingly irrefutable premise. Such tools, it has been pointed out, make early and effective treatment possible, benefiting both patients and public with faster and more frequent cures, and […]

As WHO TB report shows 3 million undiagnosed and cites drug-resistance “public health crisis,” physicians urge Obama to increase funding

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Three million people sick with tuberculosis go undiagnosed each year, while failures to address strains of disease that don’t respond to drugs constitute a public health crisis, according to the World Health Organization’s just released 2013 Global Tuberculosis Report. While the report cites progress in continued drops in TB incidence and deaths, it emphasizes that […]

Budget cuts endanger the CDC’s Tuberculosis Research Program

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The following is a guest post by Coco Jervis, senior U.S.and global policy associate Treatment Action Group , the science-based treatment advocacy organization. According to the World Health Organization, an estimated 8.7 million people became sick with tuberculosis in 2011, and more than 1 million are expected to die of the disease this year alone. […]

WHO’s TB chief: ‘We have to be bold’

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Dr. Mario Raviglione has been the director of the World Health Organization’s Stop TB Department since 2003. He spoke with John Donnelly about his frustrations with detecting cases of multidrug-resistant TB as well as with delays in accomplishing widespread availablity of the GeneXpert machine, which can detect drug-resistant TB in two hours, compared to two […]