Category Archives: Research and Development

Dengue vaccine candidate protects fully in controlled human challenge trial

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Findings, process can further vaccine quests, researchers say An experimental vaccine against dengue completely protected the 21 volunteers  who received it and were subsequently exposed to the virus, while the 20 volunteers who received a placebo instead developed infection after exposure, a study published today in Science Translational Medicine found. Researchers who conducted the human challenge trial say the results bode well […]

AIDS vaccine update: With Thai trial, broadly neutralizing antibodies, new technologies and monkeys that met the SIV challenge, “we’re closer than ever”

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NIH AIDS Vaccine Research Program Director: “The future of HIV-1 Vaccines is bright.” In 1997, scientists announced the birth of Dolly the cloned sheep, a computer named Deep Blue beat reigning chess champion Gary Kasparov, and the Hubble telescope brought the far reaches of outer space closer. President Bill Clinton pointed to all of these […]

Fauci: HIV imaging yields “significant advance” in vaccine inquiry

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For 15 years scientists have worked to get a clear enough picture of how the protein surrounding the virus that leads to AIDS interacts with antibodies, to guide the development of a vaccine that would instigate an effective immune response. For years, the delicate and complicated structure of that protein has made that difficult, and […]

Study yields clues on HIV strains with “evolutionary advantage” that can guide vaccine development

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While the virus that leads to AIDS has long been recognized to be “sloppy” in its replication, changing over time into divergent strains,  a National Institutes of Health-funded study recently found the virus that a person transmits tends to continue to look like the virus that originally infected that person. The study, significant for the […]