Category Archives: Research and Development

Report proposes innovative approaches to spurring global health innovations

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In 2003, a study published in the journal Nature told of a vaccine candidate that showed promise against Ebola when tried on monkeys. With funding or financial incentives, and the interest those might have prompted from large pharmaceutical companies, the next step would have been the development of the vaccine for use in humans, Dr. Peter Hotez of […]

Dengue vaccine candidate protects fully in controlled human challenge trial

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Findings, process can further vaccine quests, researchers say An experimental vaccine against dengue completely protected the 21 volunteers  who received it and were subsequently exposed to the virus, while the 20 volunteers who received a placebo instead developed infection after exposure, a study published today in Science Translational Medicine found. Researchers who conducted the human challenge trial say the results bode well […]

Antibiotic resistance posing little understood global health threat, WHO report says

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Survey responses across 12 countries, six regions show range of awareness, common dangers, failures to communicate . . . On the positive side, two-thirds of a sampling of people across the world are aware of antibiotic resistance and that it can affect them. On the more concerning side, three-quarters of those surveyed thought it was […]

Long-acting injectable HIV treatment shows promise in early study results

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A future of HIV treatment that doesn’t depend on daily dosing seemed to move a little closer today with an announcement that early findings show an injected combination of two antiretroviral medicines given monthly or every two months effective in controlling HIV among people whose virus was already suppressed. The findings come from the first […]

Accessible global health innovations critical to achieving Sustainable Development Goals

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“You can design the most beautiful vaccine or other technology but without proper marketing or dissemination, it will sit on a shelf,” Kaitlin Christenson of PATH said Wednesday. Emphasizing that access and affordability are key to the success of innovations addressing global health concerns, she was speaking at  a Congressional panel focused on the role […]

Development goals should include measures of global health research, report argues

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A new report calls on the United Nations to include global health research and development indicators in the Sustainable Development Goals monitoring framework, set to be adopted later this month. While the SDGs include ambitious targets for reducing child and maternal deaths and eradicating the HIV/AIDS, tuberculosis and malaria epidemics, the report notes, no indicators […]

Tuberculosis R&D “grossly insufficient” according to new report

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The global tuberculosis response and TB research and development remain weak and inadequate despite approval of the first new TB drugs in decades and a new global strategy to reduce TB incidence and mortality, according to Treatment Action Groups’ latest report. With just $255 million spent on TB research and development each year, funding is […]

Study finds diversity in costs, support, and implementation of recommended antiretroviral treatment monitoring

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It’s the best way to ensure antiretroviral treatment is working for those getting it, protecting their immune systems and preventing illness and transmission — and the alternative is more costly. Yet a World Health Organization published study of how frequently antiretroviral treatment programs in seven countries across the Americas check their patients’ viral loads and […]

Ebola vaccine, projections, quarantines, impact — a year after a public health emergency was recognized, we’re reading about results

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This week sees the end of a year since the World Health Organization Emergency Committee on the 2014 Ebola outbreak in west Africa met for the first time, and declared the epidemic to be a “public health emergency of international concern.” As of that week last August, the spread of the largest ever recorded outbreak […]

IAS 2015: HPTN 068 and CAPRISA 007 cash incentive studies show value of school, financial support, but also show more is needed to protect young people from HIV

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VANCOUVER, Canada –  Two clinical trials evaluating the impact of cash incentives on HIV incidence in adolescents  in South Africa found that such incentives had no impact on HIV rates  while one saw a decrease in rates of herpes simplex virus. Nearly 3,000 South African high school students in 14 schools in high HIV incidence […]