Category Archives: TB

TB preventive therapy reduces death, disease among HIV positive patients

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Results from a new study in Brazil show that not only is tuberculosis (TB) preventive treatment safe and effective, but it also shows significant benefits at the community level.

Announced at the 2011 International AIDS Conference in Rome, the THRio (TB and HIV in Rio) study investigators implemented clinical staff training on the importance of preventing TB in people living with HIV, and teaching doctors and nurses how to perform testing for TB infection. Scientists at Rio de Janeiro Municipal Health Secretariat in Brazil and the John Hopkins University studied these interventions in 29 clinics in Rio de Janeiro, including almost 13,000 HIV-positive patients, to determine the impact of isoniazid preventive therapy (IPT) on rates of TB and death in that population.

The intervention had a modest impact (13 percent reduction) on TB, but showed an important and statistically significant impact on TB and death that might be attributed to TB (28 percent reduction)…